All over the world, pretty and athletic girls in their teens are disappearing one after another. Behind these abductions is the mysterious Madame M, who plans to train these girls in the arts of seduction and assassination, and turn them into professional killers. After six years of grueling training, only Charlene and Jill survive to become the world's most sought after killers. On a recent mission to assassinate someone in Hong Kong, Charlene is shocked to see her mother, and comes face-to-face with CIA Agent Jack, who has been on the missing teens case since the beginning. Jack vows to help her reclaim her past, and put an end to Madame M.