3 DVDs, 1-24 (END)
The story takes place in the year 1920 in the United States of America. Paid to exterminate demons, Chrno and Sister Rosette are professional exorcists from the Magdala Monastery. They travel between various places to prevent demons from taking possession and haunting various things that come from outside the U.S.A.
One day, Rosette was given the orders to investigate a "demon master" known as Ricardo who was a wealthy American. Infiltrating the hotels that Ricardo possessed, they meet a young girl named Asmaria who was captured by him. She had a special power that allowed her to get near gods using her singing. As her power got discovered, it meant people around her always felt uncomfortable. And so, she was always alone.