- 52nd Television Drama Academy Awards: Best Drama
- 2007 Annual Drama Grand Prix Awards: Best Supporting Actor - Oguri Shun
- 16th Hashida Awards: Rookie of the Year - Oguri Shun for 'Hana Yori Dango 2'
- 16th Hashida Awards: Rookie of the Year - Inoue Mao for 'Hana Yori Dango 2'
- 10th Nikkan Sports Drama Grand Prix (Jan-Mar 07): Best Drama
- 10th Nikkan Sports Drama Grand Prix (Jan-Mar 07): Best Actress - Inoue Mao
- 10th Nikkan Sports Drama Grand Prix (Jan-Mar 07): Best Supporting Actor - Matsumoto Jun
His second season of Hana Yori Dango picks up right after Domyoji leaves for New York. After confessing to Domyoji, Makino has not spoken to him for a year. Rui and the other members of F4 try and help Makino meet Domyoji again by going to New York for the christmas holidays. Though F4 and Makino meet Domyoji again, he has become a completely different person, and so they leave for Japan.
Some time later, Domyoji's mother annouces that they will be returning to Japan. There, they hold a giant super-rich and classy birthday party for Domyoji and annouce something very important. Domyoji, like in the first season, is engaged to a rich girl and heir. The only difference is that they are to be wed soon. What will Makino do?